Apparently red is the first colour our eyes see and also the last seen when sight goes, in fact blue light is more likely to be a problem than red, red light is said to be easier on the eye.
I suppose brighness and personal preference do play a part, but I never had a problem with the red screen myself, but I do remember some people complaining about it before I got my MD so I was half expecting it to be fatiguing.
When I changed the screen on my monomachine I cut the old one off very carefully with fine sidecutters pin at a time, then used a heated solder sucker to remove the pins from the PCB. It was tricky and time consuming though.
That adafruit screen looks nice!