The OT definitely hates having a USB cable plugged in when it isn’t in USB disk mode. Just having a cable attached is enough to make it crash, so I only have mine plugged in when I need USB disk mode.
Not sure how this might be related, but I’ve run into weird LFO issues as well, detailed here:https://www.elektronauts.com/t/ot-lfo-pattern-change-issue/176131
Never figured out what the problem was, but reloading the Part kicked the LFOs back to where they were supposed to be. Not a solution, exactly, but your issues and mine might be related to the same bug.