Overbridge slows down Ableton completely

I have a brand new syntakt and trying to setup everything with Ableton Live (11-latest) on my Mac mini M1, 16GB with os x 13.5.2
After 30-45min. working fine, Ableton gets completely slow, every mouse click or interaction with the software takes several seconds to complete.
It seems independent from the plugins/effects I’m using.
Anyone else having this issue or solved it already?

I’m not talking about latency or problems with midi. After restarting Ableton Live The whole setup is working fine, using the overbridge plugin and 8 tracks routed into separate audio tracks.

Thanks for any hint.