I think things have moved on since I did it - there was a patch for midi that had to be used but I believe that is now possibly not required - I think if I was starting to get the windows .exe running on mac I’d be looking for a simpler solution via winebottler (i indeed used this recently for a different windows program with some success, not a midi program though)
The only source I know of for info on the hacky approach to running wine (without using bottler, which itself still requires some decision making and research) is via the pages on Nord Modular at Electro Music - just Google Electro music Nord Modular wine patch or similar and you’ll find discussions with the author of the patch - even that required a bit of investigation elsewhere in terms of the wine side iirc … it’s doable and worth it, I think I had to reach out on a wine forum to get a few issues sorted
but see if you can find anyone on the Nord mod Facebook page (or Electro music) who has done a recent install using winebottler or indeed any program using MIDI successfully