I use one 2880 but no footswitch as a sort of multitrack and extra mixer with its own set of fx as part of my studio setup, and live too when it comes in handy for the aux in to allow a little synth like a Monotron Delay or BC-8 to be added into the mix.
I tend not to sample into it very much (mostly for practical setup reasons as the flight case it lives in makes access to the front panel a bit fiddly), but use it for running backing tracks, environmental recordings and drum loops into whatever else is going on.
Currently it’s triggered by the A4 and passes MIDI through to a modded Volca Bass which in turn sequences an SV-1 and is synced to an SQ-1 that controls a number of other things (currently 0-Coast, Erebus, an analogue kick device and occasionally an MS-20). The 2880 might not get used all the time, but it is invaluable to have it as an option.
I’ve not really taken advantage of the 2880’s MIDI control as much as I could and a footswitch would be useful, if bulky for live use, but it’s an incredibly flexible addition to my setup. I do wish I had the later EHX 45000 looper with the SD card though, mostly as it can swap between different sets of loops stored on the card, which the 2880 cannot.