From my experience, if you want to switch to Linux, it’s better to start with an audio/music dedicated distribution. They are optimized and come with pre-installed low latency cores and necessary drivers & softwares.
To answer the comment above, i reckon the terminal don’t look appealing at first but when you know you can update all softwares on board with a simple command line, it’s really enjoyable.
On Windows for instance, you would spend ages to: know what’s outdated, find out what are your drivers, find the packages, get and install them, clean the mess… then it’s still messy.
Linux is for me like a car: the more you are interested into mechanic, the more you can taylor it to your own needs… then it works!
One word on RME: i use a Babyface Pro which is compliant … but the software TotalMix to get a total access to Routing, Fx, mixing is really limited when used in this mode. On iPad, FX are disabled and on Linux, you simply don’t have the software. You need to use workarounds and still i never got full access as on the full version.