I’ve always gone by feel & sound… I don’t use step sequencers & I almost always leave a little air before each sample (even when using synths to make sounds I sample them) that way when using quantize I can adjust the start point of the sample. For example when quantizing hi-hats I like them to hit a little late, so while the sequence is playing I adjust the start point until it sounds nice to my ears.
In my opinion going by feel & sound is the best way to get a really nice groove… & setting up the sounds so they’re easy to manipulate… that way you can adjust & experiment with the placement of the sound on the grid easily until it sounds right to you.
When I first got into electronic music I used a sp404 & made tracks in resample mode only (no sequencer). This really taught me to use my ears & feel the rhythm. For the first few months I concentrated on drums /rhythm. I started by making simple beats (sample myself playing a simple rhythm with kick & snare, then looped it), then I played with delay settings on different kick & snare hits within the loop to come up with new rhythms & would also add hits here & there. As I progressed I added more percussion, I started combining different sounds (for example using 2 hi hats instead of 1, using 2 snares, 1 short & 1 long & using 2 kicks, smaller kicks for the ghost hits) & I got better at timing (finger drumming).
I think experimenting & not using quantize helped me the most. Especially when it came to getting the groove to sound the way I like