Analog Heat +FX usb audio routing

Hi there!
I am planning to buy analog heat +fx to use it with my hardware synths and epiano and also thinking about replacing my current audio interface with it
But I cannot wrap my head around usb class compliant setting in the manual
Can I set it up that way that audio coming from usb audio is unaffected by heat or fx blocks and only devices connected to analog in going thru effects?

i’d like to know this too!