Just adding to the soup. Same problem for me.
Windows 10
Studio One 5 Pro DAW
One wrinkle that maybe bears mentioning…I don’t get random stops if I start playback from the DAW transport buttons (Studio One 5 Pro is my DAW). In this case, my DAW is rolling, of course. But if I start playback using the hardware transport buttons on the Rytm II, while Overbridge is connected, the DAW doesn’t roll, but the Rytm II does. In this situation, I get the random stops. However…if I start playback from the DAW transport buttons, I don’t get random stops, but I still get weird tempo variation now and then…usually preceded by a glitch in the beat…then pitch and tempo sometimes vary a bit while playing…by “a bit” I mean way noticeable…usually, but not always, triggered by hitting the pads. But sometimes while just staring and not touching…
If I disconnect USB cable entirely, and just go stereo outs into my interface…5-pin DIN MIDI sync from DAW using E-RM Multiclock with audio signal for sync… everything works perfectly. But, of course…no Overbridge.