No. Samplers are wonderful machines, that can take you as close to, or as far from the source as you want to. Check this out for example, from the album System Error – Nothing
“The album is called ‘nothing’, because that’s essentially what it was derived from. We wanted to reveal the hidden voice of sampling technology and play the samplers rather than the samples. Using no input signals at all, we just sampled nothing and looked really closely at it. We used every glitch and software fault and tried to listen to what the machines had to say.”
Spoiler: All off an E-Mu sampler afaik.
I’ve done stuff like this, working off just a single sample, and seeing where it can take you. But that is an exercise in stuff and things, and rather then turning that garbage truck backing up beep into that string quartet, why not just use the string quartet?
Plus I would rather do such exercises on a more dedicated sampler, like an E-Mu
And check out this by our very own Elektronauts: Octatrack Metronome Only Warp Experiment Science Lab