not that weird, that (and try test mode) would’ve been my first suggestion
there are a number of ways to affect sound output, too many to go through at the mo, but for peace of mind always try starting afresh - another possibility, though less common on analogs compared to say OT is to consider that a corruption could’ve taken place
a new project sorts most issues like this so the user can go back to teh source issue and investigate all the options. performance macros, etc etc
people resort to factory and empty resets for all the wrong reasons normally and just because the issues goes away it gets believed to be the solution, but a new project is the simplest acid test
also disconnect the machine from everything (check, you did), set it to all the regular default modes and just go through all the options, channels. settings and modulators and macros etc and see if you can pinpoint it
had a similar problem last week, about 14 patterns in a project that seemed to be silent on playback. couldn’t work out what was wrong, started to freak out I’d saved the project wrong and lost everything. Turned out I had transpose on somehow, and everything was many octaves too low lol
(not saying this is what caused your problem at all, but something to look out for!)