Actually few software developer decided to give up on development because of the SIP… some other continu updates but not want to work on a SIP Sierra Ready version and give to their owner the possibility to continu to use their software but to their own security responsibility. I have not for now TRIED that… but i will… I just recommend to the one who want to try that to WAIT A BIT THE NEW UPDATE 10.12.1 as Developer have 6 days ago the 10.12.1 beta 4 pushed ! New Macbook Pro coming later this fall (haha remembering another thread and make me smile anyway) with 10.12.1 installed as factory state.
In every case Mac Operating System is considered stable with the magic number 5 (10.11.5 ; 10.12.5)
But 10.12.1 seem to be a good starting point. And i guess Overbridge will not coming so late because of the release of Analog Heat, but i may make mistake here but i hope it’s coming that way. If not i will give up and stuck to ElCapitan until all is ready. In fact in my configuration i just waiting for Overbridge to make the jump. All other things i have graphic design and music studio are READY to Sierra.
Edit : i forget UAD too : Universal Audio will be releasing a software update in November 2016 which will be the first step toward full Sierra compatibility. This UAD software update will allow Thunderbolt UAD-2 and Apollo products to operate under macOS Sierra, however full testing and qualification for Sierra will come later. We plan to offer full macOS Sierra compatibility in a UAD software update in early 2017.