Since the actual hardware drive used is the same, I assume it only needs to be reformatted back to no data for this to be done. I do not have the expertise to tell you how the reformat works but I think if there is information on how, it will be on this forum. It is probably simple. You will need to determine first if there was a software upgrade which allowed sfx6 to access the +Drive, and whether original SW must be reinstalled. Then same for MD, whether it requires SW to work with the +Drive because I assume it does and it exists.
The physical change? I think it is only a screwdriver that is required, I don’t believe these drives require soldering, but again I don’t know.