Hi. You can send MIDI from the M:C sequencer over USB. The sequencer can send MIDI notes, MIDI velocity, and sequencer trig length. You can also send audio over USB.
The encoders can send specific MIDI CC when they are twisted. They can only do this in real time, so that means the sequencer cannot send CC events.
You need to determine the use with Drambo, I don’t have that information. Maybe you can try asking in the Drambo topic.