+1 on the Blokas Midihub. I use one at home and bought another one for my shared studio, it’s been so damn helpful.
OT as master clock, into Midihub’s A IN, from its 4 OUTs I send 1 to AR, A4, DN, last output goes to a Quadra Thru splitter then split to all pedals + Analog Heat (in case I want the BPM-locked LFO).
The Midihub is also my bridge between USB MIDI and hardware, sending/receiving from the computer.
It works flawlessly, haven’t had to give my MIDI config any thought after setting it up, needed a little bit of fiddling on DAWs to compensate some delay so I think the next step is to see if a separate master clock might solve that, never tried a standalone MIDI clock so no idea if it works to keep DAW and hardware 100% in sync without further DAW configuration.
Syncing all hardware isn’t so bad (I LOVE my moto midi timepiece AV USB for midi routing), but if you also want to sync everything to your daw you are going to need something like an erm multiclock or expert sleepers usamo. Recently I have been doing everything with an mpc and then only importing to a daw to do final arrangement and mixing.
Cirklon has five midi outs. so I use those. also some midi thru boxes. 'cuz I have a lot of shit.
there’s no issue using midi thru on a machine or synth, in general. it’s only when you start to cascade a ton of them that your timing can get off. or if the machines themselves are introducing latency. at that point, buy a midi thru box.
for your eurorack sequencers… well it depends upon what you’re using. some are friendly with midi/usb, some aren’t. some don’t even allow start/stop/reset messages.