Edit: sorry @sezare56 I missed that you posted this above…
Not sure if this is useful or not, but do you remember the thread a while back where a user had a similar issue? Metronome would always work but the rest of the audio not.
Finding … found!
Of course, don’t stop troubleshooting I was just reminded of this problem. I think it turned out to be hardware related. Read the thread for details.