The Rytm’s native format is 16bit 48khz. Anything else will be converted by C6, and because most software leaves artifacts doing this I would recommend getting a good sample rate converter. Check out http://src.infinitewave.ca/ for a list of comparisons. Audacity is good, especially because it’s free but it looks like the best sound quality wise are Adobe Audition and Izotope SRC which is in products like Sound Forge Pro and Sample Manager.