Yep, I’ve tried it, works well, but you will need a preamp first.

My setup:
Guitar > tube preamp > couple of effect pedals, some stereo ones at the end > cab sim > input 1-2 A4.
As already stated, put a trig with inf length to step1, then different trigs for the filters, then experiment.
Passive pickups won’t work well directly plugged in the A4.

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