Yeah, all presets, all user patches, inits etc.
I was using Hyakken’s MaxMSP based editor via USB, lots and lots of NRPN stuff going on as I was using the patch morpher/sequencer on every track.
Good news though… I had totally forgotten about the calibration routine… Cenk reminded me and this seems to have fixed the voices. Still concerned as what made it happen though as I was planning on using the patch morphing for some live work. 